To further investigate the role of SeC in myoblast transdifferentiation, we treated the stabilized myoblast cell line, C2C12, with TGF-β, which is known to induce transdifferentiation of myoblasts into myofibroblasts [22] and has a major role in inducing fibrosis in DMD muscles [23], in the absence or presence of SeC-DM. Here, TGFB1 is linked to Duchenne muscular dystrophy.