COL1A1 and Duchenne muscular dystrophy: We found that Del51 myoblasts co-cultured with SeC for 6 days in DM expressed lower levels of the fibrotic markers, COL1A1 (collagen 1A1), FN1 (fibronectin) and CTGF/CCN2 (connective tissue growth factor/cellular communication network factor 2) (Figure 6A), which play a major role in fibrogenesis, suggesting that SeC-secreted factors might inhibit the appearance of the fibrogenic phenotype in DMD muscles.