SLC25A20 and carcinoma: In NMGs, CACT immunoreactivity was moderate and characterized by few and small cytoplasmic granules (Figure 2A), whereas in CMTs 88% of G1 carcinomas had strong CACT immunostaining diffusing through the cell cytoplasm (Figure 2B), while CACT immunoreactivity decreased from G1 to G3 and from G2 to G3 carcinomas (Figure 2C–E).