In conclusion, both black garlic extracts and nanoemulsions can improve DOCA-salt-induced hypertension in rats through an increase of bradykinin concentration and decrease of aldosterone and Ang II concentrations as well as increase of NO production, while the learning and memory ability of rats can be improved through reduction of AChE activity, oxidative stress and inflammation as well as enhancement of antioxidant enzyme activity (Figure S2). This evidence concerns the gene ACHE and Hypertension.