In CRC cell lines, the anthocyanin-enriched extract of BRB can suppress cell proliferation, induce apoptosis, and decrease the activity of DNMT1 and DNMT3B, and demethylate CDKN2A, SFRP2, SFRP5, and WIF1 in the Wnt pathway [32,33]. This evidence concerns the gene SFRP2 and colorectal carcinoma.