SLC6A3 and neuroblastoma: It has been well documented that the undifferentiated neuroblastoma SH-SY5Y cell line is a good in vitro model of dopaminergic neurons for the study of neurodegeneration pathogenesis and drug screening [140], although it maintains a fast proliferative profile because it expresses specific dopaminergic markers such as tyrosine hydroxylase (TH) and the dopamine transporter (DAT) [178].