SERPINE2 and renal pelvis/ureter urothelial carcinoma: Multivariate analysis revealed that age ≥ 65 years (p < 0.001), invasion (p = 0.008), high grade (p = 0.001), distant metastasis (p < 0.001), and high SERPINE2 immunoscore (p = 0.002) were independent prognostic factors for poor OS in patients with UTUC.