However, univariate and multivariate Cox regression analysis revealed that PTX3 alone might be a better risk factor for 90-day mortality (hazard ratio = 2.58; 95% CI: 1.62–4.09; p < 0.001), although lactate and platelet count were also associated with 90-day mortality in sepsis patients, which was displayed by forest plot (Figure 5B). This evidence concerns the gene PTX3 and Sepsis.