Mutations of KDM5C (Lysine Demethylase 5C), KDM6A or Somatic SWI/SNF-related matrix associated actin-dependent regulation of chromatin subfamily B member 1 protein (SMARCB1) can lead to epigenetic modifications that are present in about 10% of non-NF2 meningiomas [20]. The gene discussed is NF2; the disease is meningioma.