The absence of additional proximal tubule transport anomalies, the unique extrarenal manifestations of development and intellectual disability; basal ganglia calcification;, ocular defects such as cataracts, band keratopathy, and glaucoma; and enamel flaws associated with incomplete amelogenesis are the only known causes of pRTA [79], and this ailment is only observed in patients who have NBCe1 mutations. This evidence concerns the gene SLC4A4 and cataract.