In terms of Yorkshire Terrier only VEGF-B gene was upregulated in metastasis-free mammary carcinoma tissue, compared to adjacent tissue (log FC = 1.4, p = 0.005) (n = 5) (Figure 3A) and with tumor stage I (n = 5) (log FC = 1.4, p = 0.006) (Figure 3C). This evidence concerns the gene VEGFB and neoplasm.