The choice to investigate these genes (Cyclin D1, Caspase 3, p62, and LC3B) was suggested on the basis of literature, in which analogue pathways were investigated [20,40,41] for RIP proteins, such as saporin-6, tested on glioblastoma cell lines, GL15 and U87MG. The gene discussed is CASP3; the disease is glioblastoma.