In the study on the correlation between gender and the incidence of TNF-antagonist induced psoriasis, subgroups were implemented by complying with age, and the 9 studies were divided into 2o groups, the adult group: OR = 1.911, 95%CI (1.085–3.366), P < .05, heterogeneity: I2 = 72.5%, the teenager group: OR = 2.087, 95%CI (1.329–3.277), P < .05, heterogeneity: I2 = 7.0% (Fig. 4). Here, TNF is linked to psoriasis.