In detail, Oncomine analysis also showed that TIMP2 was significantly down-regulated in breast carcinoma, ductal breast carcinoma, invasive breast carcinoma, invasive lobular breast carcinoma, invasive ductal and lobular breast carcinoma, mucinous breast carcinoma, and medullary breast carcinoma (Fig. 2A–H, Table 1). This evidence concerns the gene TIMP2 and invasive breast carcinoma.