Other papers reported the antioxidant effects of LUT via up-regulation of the Nrf2/HO-1 pathway and its anti-inflammatory actions through inhibition of NF-κB activity in monosodium iodoacetate-induced osteoarthritis in primary chondrocyte cells [160] as well as in LPS-activated microglial cells [161]. The gene discussed is NFKB1; the disease is osteoarthritis.