Astrocytoma and oligodendroglioma WHO grade 3, on the other hand, are tumor entities with different molecular genetic alterations (telomerase reverse transcriptase [TERT]) mutation and 1p19q co-deletion in oligodendroglioma) and prognosis, which in addition often show no significant contrast enhancement, which in turn have resulted in low scale cohorts in the respective subgroups. The gene discussed is TERT; the disease is astrocytoma (excluding glioblastoma).