More importantly, protective effect of the AR inhibitor against OVA-induced airway inflammation coincided with a significant reduction in the levels of Th2 cytokines, including IL-4, IL-5, and IL-6 and chemokines such as keratinocyte-derived chemokine, as well as granulocyte colony stimulating factor (G-CSF) and MCP-1 in broncho-alveolar lavage fluid [187], indicating a novel role for AR inhibitors in the prevention of asthma [13]. The gene discussed is AR; the disease is asthma.