GSTM1 and Parkinson disease: This strategy is not just limited to imaging Hb; it can also be extended for imaging other targets of the brain by designing fluorescent probes that are pre-delivered before adopting NIR imaging, which can be combined with the existing functional imaging as a multiplex approach to collect more information regarding the health status of the brain, especially in the case of Alzheimer’s, Parkinson’s, and other brain diseases.