TP53 and small cell lung carcinoma: After dendritic cells transduced with adenovirus expressing wild-type p53 were tested in ES-SCLC patients refractory to chemotherapy, with note of regained response to chemotherapy post progression after vaccination [59], NCT03406715 was started to evaluate the combination of these vaccine with ipilimumab and nivolumab in patients with recurrent SCLC [60,61].