NPPB and aortic stenosis: In 40 symptomatic patients with aortic stenosis, Vanderheyden et al. reported that the plasma B type natriuretic peptide (BNP) level was correlated with both systolic and diastolic WS, not with systolic function, suggesting that BNP may be an excellent screening tool for LV diastolic dysfunction in patients with pressure overload cardiomyopathy and normal systolic function [63].