The results revealed that angiogenesis, glycolysis, and EMT were the biological process most correlated with CD44 expression, while the TNFα signaling via NFκB, angiogenesis, IL6_JAK_STAT3 pathway, and EMT were correlated with TNFRSF12A in cancer cells across CRC, LC, and SCC (Figure 5A and Supplementary Table 7). Here, TNFRSF12A is linked to colorectal carcinoma.