The results revealed that angiogenesis, glycolysis, and EMT were the biological process most correlated with CD44 expression, while the TNFα signaling via NFκB, angiogenesis, IL6_JAK_STAT3 pathway, and EMT were correlated with TNFRSF12A in cancer cells across CRC, LC, and SCC (Figure 5A and Supplementary Table 7). This evidence concerns the gene CD44 and colorectal carcinoma.