ANXA6 and breast cancer: Given that ANXA6 induces protective autophagy (Chen et al., 2020; Sun X. et al., 2020), and induction of cell autophagy contributes to PTX resistance in BC cells (Zhang et al., 2015; Datta et al., 2019), we next explored whether ANXA6 overexpression promoted PTX resistance in PS-BC cells via activating autophagy flux.