To further confirm the above observations, we collected 62 pairs of clinical HCC patient samples and associated normal tissues to detect the mRNA levels of NQO1 and CAT. Indeed, 69.4% (43/62) of HCC patient samples showed relatively higher NQO1 mRNA levels than associated normal tissues (p = 0.0005, Figure 2A). This evidence concerns the gene CAT and hepatocellular carcinoma.