Interleukin 6 (IL-6), interferon gamma-induced protein 10 (IP-10), tumor necrosis factor (TNF) α and interleukin 1β (IL-1β) implicated as inflammatory factors associated with COVID-19 progression were detected in the alveoli with diffuse immune cell infiltration (Fig. 2D). The gene discussed is IL1B; the disease is COVID-19.