In which, many GO and KEGG enrichments were involved in lactose metabolism, colostrum immunity, and milk protein and fat, such as tetrahydrofolate interconversion, thermogenesis, oxytocin signaling pathway, antigen processing and presentation, primary immunodeficiency, immune system process, glycoprotein catabolic process, cGMP-PKG signaling pathway, fat cell differentiation, and MAPK signaling pathway (Supplementary Table S2). This evidence concerns the gene OXT and inborn error of immunity.