CNTN1 and chronic inflammatory demyelinating polyradiculoneuropathy: Although cell-mediated and humoral immunity likely play a role in CIDP, the etiology of the disease has not been elucidated.However, recent studies have reported that autoimmune antibodies against nodal- paranodal cell- adhesion molecules such as neurofascin-155 (NF155) (3, 4), contactin-1 (CNTN1) (5–7) and contactin-associated protein 1 (CASPR1) (8) and neurofascin isoforms (NF140/186) (9) are found among subgroups of CIDP patients.