MIF and Splenomegaly: A role of MIF in CSC-induced functional GC resistance in isolated and LPS-stimulated splenocytes in the present study is suggested by the fact that splenic MIF protein expression was increased in CSC versus SHC mice on days 15 and 16 of CSC, when severe splenomegaly and functional splenic GC insensitivity were detectable the first time.