Our data demonstrate an important and previously undescribed link between the NK cell degree of differentiation and the clinical outcome after autoHSCT of MM patients, as observed by the detrimental effect that higher frequency of NKG2A-CD57+ NK cells at +30 days and +100 days post-autoHSCT have in the PFS and TTNT of these patients. The gene discussed is B3GAT1; the disease is Miyoshi myopathy.