In fact, Chan and Buyon showed that so-called “monospecific” anti-Ro52 samples from patients with SjS and/or SLE depict anti-Ro60 reactivity and co-precipitation of the Ro60 associated hY-RNAs upon careful analysis in immunoprecipitation (32, 33). This evidence concerns the gene TRIM21 and Schwartz-Jampel syndrome.