Similarly, the tmTNF-α antibody suppressed the production of proinflammatory mediators (Supplementary Figures S4A–C), promoted the release of IL-10 (Supplementary Figure S4D), and inhibited the infiltration of macrophages, Treg cells, and MDSCs at the tumor stage (Supplementary Figures S4E–G). The gene discussed is IL10; the disease is neoplasm.