GPT and gastroesophageal reflux disease: But in our study, the mice weight showed that GER could prevent MCD-diet induced weight loss, and we detected lower level of ALT and AST in GER group, in addition, histopathological analysis showed that there was less vesicular steatosis, ballooning degeneration of hepatocytes, and fibrosis around hepatocytes and sinuses in the liver of the GER group.