DISC1 and schizophrenia: Other genes that are involved in early neurodevelopment and maturational processes, such as the Disrupted-in-Schizophrenia 1 (DISC1) gene, appear to exert delayed behavioral and neurochemical effects following pre- and perinatal insults in mice, with measurable effects only appearing after puberty, clearly mirroring the developmental trajectory of schizophrenia in humans (Niwa et al., 2010).