The Janus kinase (JAK) belongs to the family of family of tyrosine kinases and contains four members such as tyrosine kinase 2, JAK1, JAK2, JAK3, and functions as a regulator of signaling pathways activated by a number of growth factor and cytokines [10].Among them, JAK2 kinase plays key roles many neoplastic diseases and is extremely expressed in numerous cell types [10]. This evidence concerns the gene JAK2 and neoplasm.