PDPN and inflammatory bowel disease: Gene expression analysis of FACS-sorted cell populations from inflamed tissue from patients with IBD confirmed that several M4/M5 genes were highly expressed in CD16hi neutrophils and podoplanin (PDPN)+THY1+ stromal cells (Extended Data Figs. 5a,b and 3c; see Extended Data Fig. 6 for patient cohort details).