PheWAS analysis of the eight candidate susceptibility genes revealed that four candidate genes (CYP19A1, EIF2AK4, EVI2A and SNX11) associated with 56 traits related to seven phenotypic categories: anthropometric, bone health, cardiovascular, diabetes, hematopoiesis, liver function, and sex hormones (Supplementary Table 3). Here, CYP19A1 is linked to diabetes mellitus.