EIF2AK4 and endometrial cancer: S-MultiXcan-colocalization and MR-JTI analyses also suggested tissue-specific associations for expression of AC021755.3, EIF2AK4 HEY2, and SKAP1. The association of AC021755.3 with endometrial cancer risk was specific to predicted gene expression in the uterus, an organ whose lining consists of the endometrium.