IHC showed that the tumor cells of IPMN component were MUC2- (Fig. 3d), MUC5AC- (Fig. 3e) and CDX2-positive (Fig. 3f) but MUC1- and MUC6-negative (data not shown). The gene discussed is CDX2; the disease is pancreatic intraductal papillary-mucinous neoplasm.