One of the isoforms, ENST00000212355 (gene TGFBR3) from a combination associated with survival, is targeted by miRNA - hsa-let-7c-5p, which is known to be a tumor suppressor and acts by downregulating TGFBR3 post transcriptionally [33] (Fig. 4a). This evidence concerns the gene TGFBR3 and neoplasm.