GPT and fatty liver disease: 98A. muciniphila supplementation also decreased the levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST), and alleviated liver histopathological damage in a mouse model .99 Kim et al. recently reported that oral administration of A. muciniphila prevented fatty liver disease by regulating the expression of genes that regulate fat synthesis and inflammation in the liver.34 Moreover, different genotypes of A. muciniphila, isolated from human stool samples, played different roles in HFD-induced hyperlipidemia and liver steatosis.