In particular, leukocyte-derived (CD45+lMVs), endothelium-derived (CD31+CD42−eMVs), platelet-derived (CD31+CD42+pMVs), erythrocyte-derived (CD235a+ ErMVs), and annexin-V+ MVs significantly increased in plasma of patients with subgroups of CHD, including stable angina (SA), unstable angina (UA), and MI (NSTEMI and STEMI) [53–55]. Here, PECAM1 is linked to angina unstable.