The Ingenuity Functional Analysis tool reported differences in a Bacterial Infections function (based on differential expression of ADGRE5, C1QA, CAPG, CBY1, CCL8, CD1B, CHIT1, CLEC12A, DEFA1, F3, FCGR1A, GCA, IL1RN, IRF3, ITGB2, MMP12, MMP8, MSR1, MXI1, NSG1, POR, SERPINE1 and TNFRSF1A) as the most significant (associated p-value of 7.7E-08) functional difference between the two genotypes at baseline. This evidence concerns the gene IRF3 and bacterial infectious disease.