When LTPR was the dependent variable in a multivariate logistic regression model, the independent variables were leukocyte count, hs-CRP and the significant factors in univariate analysis (sex, age, smoking history, diabetes mellitus, cerebrovascular disease history, prior PCI, left ventricle ejection fraction, hemoglobin, platelet count, LDL-C, TC, glucose and eGFR). The gene discussed is CRP; the disease is cerebrovascular disorder.