Regarding LINC00393, Zhao et al. found that BC cells treated with CREBBP/EP300 bromodomain inhibitors can induce the downregulation of H3K27 acetylation level, along with downregulation of LINC00393 expression, which can inhibit the growth of BC cells, indicating it may therefore be a candidate for gene therapy approaches to BC (31). This evidence concerns the gene LINC00393 and breast cancer.