CDKN1A and hepatocellular carcinoma: Loss of ARID1A activates the transcription of p21 (CDKN1A) that subsequently upregulates the expression of LncRNA MVIH (lncRNA associated with microvascular invasion in HCC), which in HCC enhances angiogenesis and serves as a potential predictor for the poor recurrence-free survival of HCC patients after hepatectomy (35).