PAMR1 and cancer: Additionally, the expression of PAMR1 was also decreased in a variety of cancer types, such as colon adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), and rectum adenocarcinoma (READ) (Supplementary Figure S1D).