MCM3 and brain cancer: Figure 1(a) presents the expression of the MCM3 across cancers. The results showed that MCM3 expression was higher in several cancer groups than in normal tissues, including the bladder, brain, breast, cervical, colorectal, liver, head and neck, and lung, as well as lymphoma. However, the mRNA expression of MCM3 was significantly downregulated in leukemia and brain cancers. Moreover, we further used TIMER to evaluate the expression of MCM3 in TCGA.  Figure 1(b) shows the details of MCM3 expression across cancers.