NLRP3 and Ureteral obstruction: Liang et al. [10] reported that huayu jiedu recipe (HJR) (Astragalus membranaceus, vinegar turtle shell, batryticated silkworm, black tip snake, earthworm, radix paeoniae rubra, Salvia miltiorrhiza, radix scutellariae, honeysuckle, dandelion, and rhubarb) could downregulate mDCT-induced NLRP3 inflammasome expression in rat kidneys with unilateral ureteral obstruction (UUO) and renal tubular epithelial cells, regulate the NLRP3-caspase-1-IL-1βaxis/IL-18 axis, inhibit pyroptosis, and antagonize inflammatory lesions, thus slowing the progression of obstructive nephropathy.