A study claims that tumor-associated mesenchymal stem-like cells (tMSLCs), presumably as reminiscent of fibroblasts in other tumors, correlate with the poor prognosis of the GBM and enhance the invasiveness of GBM by force-mediated ECM remodeling through CCL2/JAK1/MLC2 signaling (125). This evidence concerns the gene CCL2 and glioblastoma.