UBA1 and cutaneous vasculitis: Interestingly, an adult-onset autoinflammatory disease associated to UBA1 somatic mutations was recently described in 25 patients, 24% showing MDS and 88% having skin involvement with lesions such as nodules and plaques (compatible with neutrophilic dermatosis or cutaneous vasculitis), periorbital swelling, and severe cutaneous reaction to anakinra injection (21).