STAT3 and hematopoietic and lymphoid cell neoplasm: STAT3 in particular has been implicated in a number of other cancers including those arising from epithelial cell lines such breast cancer, lung cancer, bladder cancer as well as hematologic cancers and aberrations such as acute myeloid leukemia, diffuse large B-cell lymphoma, large granular lymphocytic leukemia, aplastic anemia, and myelodysplastic syndrome (18).