NFKB1 and heart failure: The identified compounds with their pharmacological activities are 2,4-dinitro-N2, N3-dipropyl-6-(trifluoromethyl)-1,3-benzenediamine was known for an agonist for β-adrenergic receptor and activate AMPK level, gibberellic acid, digitoxin (heart failure treatment), gamabufotalin (suppress COX-2 via Iκκb/Nf-κb signaling), colchicine (decrease blood uric acid level), belcomethasone (used as mucolyte), dehydrocholic acid, prednisone, β carotene, levodopa, tetradecanoic acid, cortisone, retinol, 2-deoxy guanosine, triaziquone, phenylmercuric salicylate, prednisone, retinyl acetate, and vincamine.