As shown in Figure 8A, 1, 2, 10, and 100 ng/ml IL-1β stimulation apparently enhanced the cell proliferative viability of HFLS-RA (compared with the Blank group, p < 0.001, 0.01, 0.05, and 0.05, respectively), indicating that IL-1β can induce HFLS-RA proliferation. Here, IL1B is linked to rheumatoid arthritis.